Overview
David Eichhorn is the associate dean for faculty development and research and a professor of chemistry. His activities in the dean鈥檚 office include assisting faculty in applying for and managing external research funds, coordinating and advising faculty applying for tenure and promotion, facilitating the Watkins Visiting Professor series, addressing faculty personnel issues, and overseeing college committee elections, sabbatical applications, new faculty mentoring, and faculty annual reviews. He serves as the college鈥檚 liaison to the University Research Office.
Dr. Eichhorn started his career as an assistant professor of chemistry at 麻豆传媒映画出品 State in 1996, with promotions to associate professor in 2002 and professor in 2009. He has served as associate dean of the graduate school (2005-2008) and as chair of the department of chemistry (2008-2018). Dr. Eichhorn has authored more than 60 papers in bioinorganic and transition metal chemistry.
Originally from the Maryland suburbs of Washington, DC, Dr. Eichhorn earned a Ph.D. in inorganic chemistry from the University of California, Berkeley, in 1992 and a bachelor of arts in chemistry from Harvard University in 1986. Before coming to 麻豆传媒映画出品 State, he completed four years of postdoctoral research at Northwestern University.
Information
Metalloenzyme active sites, Transition metal scorpionate complexes
Inorganic Chemistry
- CHEM 514: Inorganic Chemistry
- CHEM 615: Advanced Inorganic Chemistry
- CHEM 616: Inorganic Chemistry Laboratory
62. Freige, M.J.; Senaratne, N.K.; Eichhorn, D.M.; 鈥�(2-{[2-(Dimethylamino)ethyl]iminomethyl}benzenethiolato-魏3N,N鈥�,S )(4-methoxybenzenethiolato-魏S)nickel(II)鈥� ; IUCrData 2018, 3, x181167.
61. Oberley, A.J.; Kadel, L.R.; Senaratne, N.K.; Eichhorn, D.M.; 鈥淭etraethylammonium (acetonitrile)trichloridopalladate(II)鈥�; IUCrData 2018, 3, x180750.
60. Senaratne, N.K.; Mwania, T.M.; Moore, C.E.; Eichhorn, D.M.; 鈥淣i complexes of N2S ligands with amine/imine and amine/amide donors with relevance to the active site of Ni Superoxide Dismutase鈥�; Inorg. Chim. Acta 2018, 476, 27-37.
59. Meloccaro, A.; Zimmerman, J.R.; Eichhorn, D.M.; 鈥淏is{2-[({[3-(dimethyl-azaniumyl)propyl]imino}-methyl)phenyl]sulfanido}nickel(II) tetraphenylborate鈥�; IUCrData 2017, 2, x171067.
58. Rillema, D.P.; KomReddy, V.; Senaratne, N.K.; Eichhorn, D.M.; 鈥淢ethyl 5-methylpyrazine-2-carboxylate鈥�; IUCrData 2017, 2, x170997.
57. Rillema, D.P.; KomReddy, V.; Senaratne, N.K.; Eichhorn, D.M.; 鈥�(2,2鈥�-Bi颅pyrazine-魏2N1,N1鈥�)摆1,2-产颈蝉颅颅(诲颈颅辫丑别苍测濒颅辫丑辞蝉辫丑补苍颅测濒)尘别迟丑补苍别-魏P]tri颅carbonyl颅rhenium(I) tri颅fluoro颅methane颅sulfonate monohydrate鈥�; IUCrData 2017, 2, x170935.
56. Panja, A; Jana, N.C.; Bauz谩, A; Adak, S.; Eichhorn, D.M.; Frontera, A.; 鈥淚ntroducing supramolecular interactions into robust bis(tetrabromocatecholate) chelated manganese(III) systems and biomimetic catalytic activity鈥�; Chem. Select, 2017, 2, 2094-2105.
55. Kadel, L.R.; Kromer, J.R.; Moore, C.E.; Eichhorn, D.M.; 鈥淣ew trisubstituted cyanopyrazoles and cyanoscorpionates鈥�; Polyhedron 2017,125, 206-218.
54. Kadel, L.R.; Bullinger, J.C.; Baum, Robert R.; Moore, C.E.; Tierney, D.L.; Eichhorn, D.M.; 鈥淐yanoscorpionate Ligands: Agostic Interactions in a Series of Metal Complexes Containing the Tris(4-cyano-3-phenylpyrazolyl)borate and Bis(4-cyano-3-phenylpyrazolyl)borate Ligands鈥�; Eur. J. Inorg. Chem. 2016 2543-2551.
53. Sullivan, M.T.; Senaratne, N.K.; Eichhorn, D.M.; 鈥淪ynthesis and X-ray Crystallographic Characterization of [In(tsalen)(OAc)] (tsalen = N,N'-Ethylenebis(thiosalicylideneimine))鈥�; Polyhedron 2016, 114, 152-155.
52. Panja, A.; Jana, N.C.; Patra, M.; Brand茫o, P.; Moore, C.E.; Eichhorn, D.M.; Frontera, A; 鈥淰alence tautomerism induced nucleophilic ipso substitution in a coordinated tetrabromocatecholate ligand and diverse catalytic activity mimicking the function of phenoxazinone synthase鈥�; J. Mol. Cat. A 2016, 412, 56-66.
51. Panja, A.; Eichhorn, D.M.; 鈥淎 linear S-bridged trinuclear cobalt(III) complex with 2-aminobenzenethiol: synthesis, crystal structure, and spectroscopic characterization鈥�; J. Coord. Chem. 2013, 66, 3037-3044.
50. Lai, H.; Dou, D.; Aravapalli, S.; Teramoto, T.; Lushington, G.H.; Mwania, T.M.; Alliston, K.R.; Eichhorn, D.M.; Padmanabhan, R.; Groutas, W.C.; 鈥淒esign, Synthesis and Characterization of Novel 1,2-Benzisothiazol-3(2H)-one and 1,3,4-Oxadiazole Hybrid Derivatives: Potent Inhibitors of Dengue and West Nile Virus NS2B/NS3 Proteases鈥� Bioorganic & Medicinal Chemistry 2013, 21, 102-113.
49. Panja, A.; Eichhorn, D.M.; 鈥淢ono- and di-nuclear nickel(II) complexes with mixed N/S-donor ligands: Syntheses, structures and physical properties鈥�; Inorg. Chim. Acta 2012, 391, 88-92.
48. Johnson, D.M.; Eichhorn, D.M.; Moore, C.E.; Mwania, T.M.; Zhao, N.; Cyano-substituted bispyrazolylborates thallium(I) complexes鈥�; J. Chem. Crystallog. 2012, 42, 746-751.
47. Zimmerman, J.R.; Smucker, B.W.; Dain, R.P.; VanStipdonk, M.J.; Eichhorn, D.M.; 鈥淭ridentate N2S ligand from 2,2鈥�-dithiodibenzaldehyde and N,N-dimethylethylenediamine: Synthesis, structure, and characterization of a Ni(II) complex with relevance to Ni Superoxide Dismutase鈥�; Inorg. Chim. Acta 2011,373 54-61.
46. Andra, K.K.; Bullinger, J.C.; Bann, J.G.; Eichhorn, D.M.; 2-Fluoro-L-Histidine; Acta Cryst. 2010, E66, o2713.
45. Dou, D.; He, G.; Lai, Z.; Wei, L.; Alliston, K.R.; Lushington, G.H.; Eichhorn, D.M.; Groutas, W.C.; 鈥淯tilization of the 1,2,3,5-thiatriazolidin-3-one 1,1-Dioxide Scaffold in the Design of Potential Inhibitors of Human Leukocyte Proteinase 3; Bioorg. Med. Chem. 2010, 18, 1093-1102.
44. Eichhorn, D.M.; 鈥淎nalysis of 鈥楯anus Scorpionates: Supramolecular Tectons for the Directed Assembly of Hard鈥揝oft Alkali Metallopolymer Chains鈥� and 鈥楢 Second-Generation Janus Scorpionate Ligand: Controlling Coordination Modes in Iron(II) Complexes鈥欌��; Chemtracts Organic Chemistry 2009, 22, 135-140.
43. Bullinger, J.C.; Eichhorn, D.M.; 鈥淐yanoscorpionates: Co(II), Mn(II), and Ni(II) Complexes Coordinated Only Through the Cyano Group鈥�; Inorg. Chim. Acta, 2009, 362, 4510-4516.
42. Panja, A.; Eichhorn, D.M.; 鈥淪ynthesis and Characterization of Tetrahedrally and Octahedrally Coordinated Mixed Valence Cobalt(II,III) Complex with Thiosemicarbazone Based Ligand鈥�; J. Coord. Chem. 2009, 62, 2600-2609.
41. Dou, D.; Talaty, E.R.; Moore, C.; Bullinger, J.; Eichhorn, D.M.; Groutas, W.C.; 鈥淔ormation of an Unusual Dimeric Product in the Reaction of a 1,2,5 鈥揟hiadiazolidine 1,1 Dioxide-Derived Thioether with Sulfuryl Chloride鈥�; J. Heterocyclic Chem. 2009, 46, 669&苍产蝉辫;鈥�&苍产蝉辫;673.
40. Burns, D.H.; Meece, F.A.; Moore, C.E.; Eichhorn, D.M. 鈥淭wo similar dibenzo cyclic ethers with dissimilar conformations鈥�; Acta Crystallogr. 2009, C65, o27-o30. DOI
39. Panja, A.; Campana, C.; Leavitt, C.; Van Stipdonk, M.J.; Eichhorn, D.M. 鈥淚ron and Cobalt Complexes of 2,6-Diacetylpyridine-bis(R-thiosemicarbazone) (R=H, phenyl) Showing Unprecedented Ligand Deviation from Planarity鈥�; Inorg. Chim. Acta 2009, 362, 1348-1354. DOI
38. Zhao, N.; Bullinger, J.C.; Van Stipdonk, M.J.; Stern, C.L.; Eichhorn, D.M.; 鈥淐yanoscorpionates 鈥� Synthesis and Crystallographic Characterization of 1-D Cu(I) Coordination Polymers鈥�; Inorg. Chem. 2008, 47, 5945-5950. DOI:
37. Zhao, N.; Van Stipdonk, M.J.; Bauer, C.; Campana, C.; Eichhorn, D.M. 鈥淪andwich Compounds of Cyanotrispyrazolylborates 鈥� Complexation-induced Ligand Isomerization鈥�; Inorg. Chem. 2007, 46, 8662-8667. DOI:
36. Smucker, B.W.; Van Stipdonk, M.J.; Eichhorn, D.M. 鈥淚ncorporation of Thiolate Donation Using 2,2'-Dithiodibenzaldehyde: Complexes of a Pentadentate N2S3 Ligand With Relevance to the Active Site of Co Nitrile Hydratase鈥�; J. Inorg. Biochem., 2007, 101, 1537-1542. DOI
35. Zhao, N.; Van Stipdonk, M.J.; Eichhorn, D.M. 鈥淪yntheses and Crystal Structures of 3-tert-butyl-4-cyano Pyrazole and its Complexes with Cobalt(II), Manganese(II), and Copper(II)鈥�; Polyhedron, 2007, 26, 2449-2454. DOI
34. Kirgan, R.; Moore, C.; Eichhorn, D.M.; Rillema, D.P. 鈥�4-Acetylresorcinol鈥�; Acta Cryst. 2007, E63, o4252. DOI
33. Zhao, N.; Eichhorn, D.M. 鈥淒ichlorobis(3,5-dimethylpyrazole)copper(II)鈥� Acta Cryst. 2005, E61, m822-m823. DOI
32. Villegas, J.M.; Stoyanov, S.R.; Moore, C.E.; Eichhorn, D.M.; Rillema, D.P. 鈥�fac-Tricarbonyl(2,9-dimethyl-1,10-phenanthroline)(2,6-dimethylphenyl-isocyanide)rhenium(I) hexafluorophosphate鈥� Acta Cryst. 2005, E61, m533-m534. DOI
31. Zhong, J.; Lai, Z.; Groutas, C. S.; Wong, T.; Gan, X.; Alliston, K. R.; Eichhorn, D.; Hoidal, J. R.; Groutas, W. C. 鈥淪erendipitous Discovery of an Unexpected Rearrangement Leads to Two New Classes of Potential Protease Inhibitors鈥� Bioorg. Med. Chem. 2004, 12, 6249-6254.
30. Oshin, K.; Landis, A. M.; Smucker, B. W.; Eichhorn, D. M.; Rillema, D. P. 鈥�fac-Bipyridyltricarbonyl(pyridine)rhenium(I) trifluoromethanesulfonate鈥� Acta Cryst. 2004, E60, m1126-m1127. DOI
29. Eller, C.; Smucker, B. W.; Kirgan, R.; Eichhorn, D. M.; Rillema, D. P. "5,5'-Dimethyl-2,2'-bipyrazine"; Acta Cryst. 2004, E60, o433-o434. DOI
28. Siemer, C. J.; VanStipdonk, M. J.; Kahol, P. K.; Eichhorn, D. M.; "A Coordination Polymer from a Cyanoscorpionate Complex"; Polyhedron 2004, 23, 235-238.
27. Eichhorn, D. M.; Goswami, N.; "New Synthetic Techniques for the Incorporation of Thiolate Donation in Transition Metal Complexes"; Comm. Inorg. Chem. 2003, 24, 1-13. DOI:
26. Vongtragool, S.; Gorshunov, B.; Dressel, M.; Krzystek, J.; Eichhorn, D. M.; Telser, J.; "Direct Observation of Fine Structure Transitions in a Paramagnetic Nickel(II) Complex Using Far-Infrared Magnetic Spectroscopy: A New Method for Studying High-Spin Transition Metal Complexes"; Inorg Chem. 2003, 42, 1788-1790. DOI:
25. Gu, W.; Jacquamet, L.; Patil, D. S.; Wang, H.-X.; Evans, D. J.; Smith, M. C.; Millar, M.; Koch, S.; Eichhorn, D. M.; Latimer, M.; Cramer, S. P.; "Refinement of the Nickel Site Structure in Desulfovibrio gigas Hydrogenase Using Range-extended EXAFS Spectroscopy"; J. Inorg. Biochem. 2003, 93, 41-51. DOI:
24. Goswami, N.; Van Stipdonk, M. J.; Eichhorn, D. M.; "Formation of an ethylene-bridged bis(benzisothiazole) dication by oxidative decomplexation of Ni(tsalen) with FeCl3"; Inorg. Chem. Commun. 2003, 6, 86-89. DOI:
23. Siemer, C. J.; Meece, F. A.; Armstrong, W. H.; Eichhorn, D. M.; "Iron, Copper, and Cobalt Complexes of Hydrotris(3-phenylpyrazolyl)borate and Dihydrobis(3-phenylpyrazolyl)borate. Synthesis and X-ray Crystallographic Characterization"; Polyhedron 2001, 20, 2637-2646. DOI
22. Siemer, C. J.; Goswami, N.; Van Stipdonk, M. J.; Eichhorn, D. M.; " Dihydrobis(4-cyano-3-phenylpyrazol-1-yl)borate: Homoleptic Mononuclear Cobalt(II) and Copper(II) Complexes With a Cyano-substituted Scorpionate Ligand."; Inorg. Chem., 2001 40, 4081-4084. DOI:
21. McCormick, B. J.; Siemer, C.; Afroz, F.; Wasson, J. R.; Eichhorn, D. M.; Scott, B.; Shah, S.; Noffsinger, K.; Kahol, P. K.; "The Copper Acetylenedicarboxylate System" Synthetic Metals, 2001, 120 , 969-970. DOI:
20. Shan, B.-Z.; Zhao, Q.; Goswami, N.; Eichhorn, D. M.; Rillema, D. P.; "Structure, NMR, and Other Physical and Photophysical Properties of Ruthenium Complexes Containing the 3,3'-Dicarboxyl-2,2'-Bipyridine Ligand"; Coord. Chem. Rev.; 2001, 211, 117-144. DOI:
19. Xue, W.-M.; Goswami, N.; Eichhorn, D. M.; Orizondo, P. L.; Rillema, D. P.; "Synthesis and Luminescence Properties of a Nonsymmetric Ligand-Bridged ReI-ReI Chromophore" Inorg. Chem. 2000, 39, 4460-4467. DOI:
18. Burns, D. H.; Chan, H.-K.; Miller, J. D.; Jayne, C. L; Eichhorn, D. M. " Synthesis, Modification, and Characterization of a Family of Homologs of exo-Calix[4]arene: exo-[n.m.n.m]Metacyclophanes, n,m鈮�3"; J. Org. Chem., 2000, 65, 5185-5196. DOI:
17. Goswami, N.; Eichhorn, D. M.; "Incorporation of Thiolate Donation Using 2,2'-Dithiodibenzaldehyde: Synthesis of Ni, Fe, and Cu Complexes. Crystal Structures of [M(tsalen)] (tsalen = N,N'-Ethylenebis(thiosalicylidene)imine); M = Cu, Ni) Showing a Tetrahedral Distortion of Cu(tsalen)"Inorg. Chim. Acta , 2000,303, 272-277. DOI
16. Depriest, J.; Zheng, G. Y.; Goswami, N.; Eichhorn, D. M.; Woods, C.; Rillema, D. P.; "Structure, Physical and Photophysical Properties of Platinum(II) Complexes Containing Bidentate Aromatic and Bis(diphenylphosphino)methane as Ligands"; Inorg. Chem. 2000, 39, 1955-1963. DOI:
15. Deviprasad, G. R.; Eichhorn, D. M.; D'Souza, F. "Crystal Structure and Intermolecular Coordination Behavior of a Porphyrin Bearing Hydroquinone Receptor, meso-Mono(hydroquinonyl)triphenylporphyrinatozinc" J. Chem. Crystallogr. 1999 29, 849-853. DOI:
14. Goswami, N.; Eichhorn, D. M.; "A New Method for Incorporating Thiolate Donors into a Metal Coordination Sphere. Synthesis and Crystal Structures of the First Nickel Complexes of an N3S Ligand" Inorg. Chem. 1999, 36, 4329-4333. DOI:
13. Wang, Y.; Eichhorn, D. M.; Goswami, N.; Zhao, Q.; Rillema, D. P.; "Crystal Structure and Physical Properties of a Ruthenium(II) Bipyridine Complex" J. Chem. Crystallog. 1999, 29, 277-281. DOI:
12. Huyett, J.E.; Choudhury, S.B.; Eichhorn, D. M.; Bryngelson, P.A.; Maroney, M.J.; Hoffman, B.M.; "Pulsed ENDOR and ESEEM Study of [Bis(maleonitriledithiolato)nickel]-: An Investigation into the Ligand Electronic Structure" Inorg. Chem. 1998, 37, 1361-1367. DOI:
11. Andersen, K.; Andersen, M.; Anderson, O. P.; Baum, S.; Baumann, T. G.; Beall, L. S.; Broderick, W. E.; Cook, A. S.; Eichhorn, D. M.; Goldberg, D.; Hope, H.; Jarrell, W.; Lange, S. J.; McCubbin, Q. J.; Mani, N. S.; Miller, T.; Garrido Montalban, A.; Rodriquez-Morgade, M. S.; Lee, S.; Nie, H.; Olmstead, M. M.; Sabat, M.; Sibert, J. W.; Stern, C.; White, A. J. P.; Williams, D. B. G.; Williams, D. J.; Barrett, A. G. M.; Hoffman, B. M.; 鈥淪tar Porphyrazines and Related Multimetallic Macrocycles鈥� J. Heterocyclic Chem. 1998, 35, 1013-1042. DOI:
10. Eichhorn, D. M.; Yang, S.; Jarrell, W.; Baumann, T.; Beall, L.S.; White, A.J.P.; Williams, D.J.; Barrett, A.G.M.; Hoffman, B.M.; 鈥淸60]Fullerene and TCNQ Donor-Acceptor Crystals of Octakis(dimethylamino)porphyrazine鈥� J. Chem. Soc., Chem. Commun.1995, 1703-1704.
9. Broderick, W.E.; Eichhorn, D. M.; Liu, X.; Toscano, P.M.; Owen, S.; Hoffman, B.M.; "Three Phases of [Fe(C5Me5)2]+[TCNQ]-: Ferromagnetism in a New Structural Phase" J. Am. Chem. Soc. 1995, 117, 3641-3642. DOI:
8. Broderick, W.E.; Eichhorn, D. M.; Liu, X., Owens, S.; Toscano, P.M.; Hoffman, B.M.; "Ferromagnetism in a New Structural Phase of [Fe(C5Me5)2][TCNQ]" Mol. Cryst. Liq. Cryst. 1995, 273, 17-20. DOI
7. Eichhorn, D. M.; Telser, J.; Stern, C.L.; Hoffman, B.M.; "Influence of Zero-Field Splitting and State Mixing on Ferromagnetic Exchange in the Integrated-Stack Charge-Transfer Salt [Cp*2Fe][Co(HMPA-B)]" Inorg. Chem. 1994, 33, 3533-3537. DOI:
6. Eichhorn, D. M.; Skee, D.C.; Broderick, W.E.; Hoffman, B.M.; "Ferromagnetism in Decamethylchromocenium tetracyanoethylenide" Inorg. Chem. 1993, 32, 491-492. DOI:
5. Eichhorn, D. M., Armstrong, W.H.; "A Remarkably Stable Mononuclear Manganese(III) Hydroxide Complex: [L1MnIII(OH)] (L1=bis(2-hydroxy, 5-nitrobenzyliminopropyl)颅methylamine)" J. Chem. Soc., Chem. Commun. 1992, 85-87.
4. Cramer, S.P.; deGroot, F.M.F.; Ma, Y.; Chen, C.T.; Sette, F.; Kipke, C.A.; Eichhorn, D. M.; Chan, M.K.; Armstrong, W.H.; Fuggle, J.C. "Ligand Field Strengths and Oxidation States from Manganese L-Edge Spectroscopy" J. Am. Chem. Soc. 1991, 113, 7937-7940.
3. Chambron, J.-C.; Eichhorn, D. M.; Franczyk, T.S.; Stearns, D.M. "Structure of [Hydro(trispyrazolylborato)-triphenylphosphinoiodomethyl] Rhodium(III)"Acta Crystallogr., 1991, C47, 1732-1734. DOI:
2. Low, D.W.; Eichhorn, D. M.; Draganescu, A.; Armstrong, W.H. "Structure and Properties of [Mn9O7(O2CC6H5)13py)2]: A Novel Nonanuclear Mn(III) Oxo-Carboxylate Species Synthesized by Employing an Oxygen Atom Transfer Agent" Inorg. Chem., 1991, 30, 877-878. DOI:
1. Eichhorn, D. M.; Armstrong, W.H. "M{(Hydrotris(3-phenyl-pyrazolyl)borate}2: Sterically Encumbered Iron(II) and Manganese(II) Complexes " Inorg. Chem. 1990, 29, 3607-3612. DOI: